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ZIOPHARM Oncology, Inc. (ZIOP)

NasdaqCM - NasdaqCM Delayed Price. Currency in USD
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6.100.00 (0.00%)
At close: 4:00PM EDT
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  • Newbie asking about comparison of Northwest Bio's DCVax versus ZIOP's "superior" Veledimex + adenoviral IL-12.

    In ZIOP's case, the studies to date have only included Phase I safety and tolerability, producing ZERO evidence of tumor efficacy or improved survival (contrary to misleading company press releases). Thus, no controlled studies, only patients that have received varying doses of the activator ligand, Veledimex (lowest dose, 20mg) and the IL-12 adenoviral vector. The patients with the longest survival in ZIOP's study received the lowest dose of Veledimex + IL-12 adenoviral vector, making it possible that patients may have faired best if they had received no ZIOP therapy (i.e. a control arm that was never studied) at all. Patients in ZIOP's safety studies also went on to take various therapies post ZIOP Safety Study, thereby confounding interpretation of survival results. Lastly, ZIOP's patients were not required to limit corticosteroid use prior and post therapy as they were in the DCVAx Phase 3 study. While a theory of reduced survival with corticosteroid use has been postulated in ZIOP's study, the data shows that the longest surviving patient, the Brain Chancery Patient - you can read his blog online, received a moderate/high doses of corticosteroids post ZIOP therapy to help save his life.

    NWBO, with their PIII studies will have definitive results on activity since there patient trial includes randomly selected GBM patients and control arms. With that said, they too have limited their patient population to patients with resectable tumors. Bottom line is ZIOP's is certainly not superior to NWBO's based on available data, and ZIOP's Veledimex/IL-12 studies have a continued long and dubious road ahead. GBM a disease that is notoriously difficult to treat,
  • Newbie here. So, can I hear some intelligent comments as to why this treatment is superior to the Northwest Bio's (NWBO) DCVax (currently in phase 3 that is almost completed)? Thanks.
  • The Rob obsession by George continues......LOL! Many on here don't even know who that is, but I bet you that he is no analyst, & probably not sold a car in decades (if he ever did that); don't get George's motivation, except that he is mad at Rob....did Rob make his investment bad or what? For all the time & money he spent attacking that dude, he could have bought a new boat or something huh? So ignorant, and it does not make anyone else sell here, since most are not so stupid. The stock is down cause "all" nearly biotech is down today, and it's on super low volume.....both ZIOP & XON have nearly exact volume - just noticed that. But obviously George will never ever get a life & never tell you his picks ahead of time.....lol.
  • So many better names in bio land to short & these obsessed mongrels keep trying on Ziopharm, even though less than a buck off of its lows; can you believe? So damn dumb!
  • at $6 per share zip is valued at 800 mill ??? with only 80 mill in bank ?

    prepare for another offering eoy.. and yes still at $5 ish ..
  • It is comical, dropping on the lowest possible volume, after all them calls bought; and you have to realize that the XBI is getting manipulated down pretty heavy to low of the day here.
  • This guy George is on every message board out there (under multiple names) & every one with a brain has him on ignore; he might as well talk to a wall, & I bet he does....lol.
  • Entire sector down. Perfect buying prices.
  • Yep, controlled by crooks (at times) it seems = you see huge call buying one day & the next MMs drive price down; so typical. Buy shares, not gamble on mega calls, even to hedge. #Dumb
  • Lots of lonely bears stalking all these message boards huh? If you so confident Ziopharm is going to fail why do you have spend so much time trying to talk people into selling???? (Am I right?)
  • I think is time to create a GoFundMe page, to raise money for its funeral.
  • Large Jan $10 call buyer, over 3K; very bold; if just a hedge, why so far out in time? They could have obtained the Oct $10 calls for ONE THIRD THE PRICE of those bought in January. Very interesting.
  • Next important date???/
  • What's ZamdTard going to do with all of those ZIOP shares he bought for $10? He bought the majority of his shares well over $9 and a large chunk at $10. That bag holder is going to take a beating like a drum.
  • Once again weak lunatic idiotic sellers not making any money; you not getting my shares you nuts!
  • The lowest of low volume hits the bid lower under $6, but stock is basically tracking the XBI index; low volume seller not making any $$$.
  • Believe it or not; that was me buying 2,720 shares. Several sources including Bloomberg are saying ZIOP is being upgraded on the next round.
  • The lowest weekly volume ever seen on the chart these last 3 weeks; Longs don't try to hit the ask to force price up, but parasite shorts sure stalk the bid every minute trying to manipulate, even if volume is the lowest of the year. Be careful, such low volume just might mean big news is about to hit!
  • Obviously same evil element trying every morning on teeny volume to push lower to paint tape....should not be legal but eventually they give it up.