IBB - iShares Nasdaq Biotechnology ETF

NasdaqGM - NasdaqGM Real Time Price. Currency in USD
-0.59 (-0.54%)
At close: 4:00PM EST

108.16 -0.49 (-0.45%)
After hours: 7:29PM EST

Stock chart is not supported by your current browser
Previous Close109.24
Bid108.14 x 2200
Ask108.49 x 1200
Day's Range108.54 - 110.66
52 Week Range89.01 - 122.97
Avg. Volume2,354,661
Net Assets7.45B
PE Ratio (TTM)3.78
YTD Return-9.53%
Beta (3Y Monthly)1.64
Expense Ratio (net)0.47%
Inception Date2001-02-05
Trade prices are not sourced from all markets
  • Aptinyx Stock Plunged 70% after Clinical Trial Failure
    Market Realist10 hours ago

    Aptinyx Stock Plunged 70% after Clinical Trial Failure

    Aptinyx Stock Plunged 70% after Clinical Trial FailureStock performance Today, Aptinyx (APTX) is trading at $5.26, which is a ~70.5% decline from yesterday’s closing price of $17.83. Also today, Aptinyx hit a 52-week low of $5.02. The company hit

  • MarketWatch14 hours ago

    Aptinyx stock falls 67% after phase 2 trial fails to meet primary endpoint

    Shares of Aptinyx Inc. fell 67% in premarket trade Wednesday after the biotech company announced that the phase 2 study of its treatment for painful diabetic peripheral neuropathy did not meet its primary endpoint. The therapy, NYX-2925, did not show a significant difference in patients' daily pain scores compared to placebo, Aptinyx said. The company said it is also conducting an exploratory phase 2 study of NYX-2925 in patients with fibromyalgia, and said a full analysis of the data should be available in the first half of 2019. Shares of Aptinyx have gained 7.8% in the year through Tuesday, while the S&P 500 has gained 4.1%. The iShares Nasdaq Biotechnology ETF has gained 13.3%.

  • InvestorPlace5 days ago

    Why Sarepta Therapeutics Stock Is Starting to Shine Again

    Sarepta Therapeutics (NASDAQ:SRPT) started 2019 with very high volatility. After spiking to around $125 a share on Jan. 7, SRPT stock gave up those gains when markets took in the developments in its DMD pipelines and its Exondys 51 fourth-quarter sales outlook. Although shares rebounded from December 2018 lows, should biotech stock investors seriously consider investing in this company? At the J.P. Morgan conference, Sarepta said it will run 45 biopsies this quarter for SRP-4045. This is an investigational compound that treats DMD or Duchenne muscular dystrophy patients with mutations in the DMD gene. The drug works by directing cells, through Sarepta's PMO, to skip exon 45 when processing RNA. The dystrophin protein is shortened but is still synthesized, slowing the negative symptoms of DMD. If the biopsies are positive, Sarepta will file a marketing application, setting up a possible approval date of early 2020. InvestorPlace - Stock Market News, Stock Advice & Trading Tips ### SRPT's Sales Outlook SRPT stock volatility rose after the company issued its revenue outlook for Exondys 51. In the fourth quarter ended Dec. 31, 2018, it made $84.4 million in revenue from sales of Exondys 51. For 2018, revenue was around $301 million. It ended that same period with a healthy balance of $1.1 billion in cash. * 10 Key Emerging-Market Stocks to Buy for Contrarian Investors Markets reacted negatively to the outlook because it expected quarterly revenue of $85.8 million. The barely $2 million difference is a rounding error and the market quickly realized it. Quarterly revenue is in line with forecasts. As markets rebounded, taking the iShares Nasdaq Biotechnology ETF (NASDAQ:IBB) up 11.5% on the week, SRPT stock also rose the same amount (11%). Sarepta's global growth plans should lower the risks of relying solely in one market: "We continue to build our international presence with limited infrastructure but dedicated colleagues in Latin America and Europe and a managed access program or MAP now live in some 44 countries. We should continue to see modest contribution from our MAP throughout 2018 with increasing contribution in 2019 and beyond." Source: SA Transcript ### Impressive Talent at Sarepta Sarepta highlighted the 25 programs in RNA and gene therapy underway. Its staff talent consists of over 500 professionals. This leading gene therapy team could deliver on bringing 3 RNA-therapies by 2020. It may potentially treat 30% of the DMD market. Historically, the team is showing that it is delivering. FY 2018 revenue nearly doubled to $301 million, up from the 2017 revenue of $154.6 million. ### Investing Opportunity Sarepta is a top five rare disease company by market cap. Only Alexion Pharmaceuticals (NASDAQ:ALXN), BioMarin Pharmaceutical (NASDAQ:BMRN) and Vertex Pharmaceuticals (NASDAQ:VRTX) are bigger. SRPT stock is underperforming compared to its peers. While the other firms' stock price traded closer to its 52-week highs after the market rally in the last few days, Sarepta is still around 33% below its yearly high. Wall Street coverage gained steam in the last few days. The company received over five "buy" calls, with a price target ranging from $161 to as high as $267. Analyst Firm Position Price Target Date Debjit Chattopadhyay H.C. Wainwright Buy $267.00 yesterday Salveen Richter Goldman Sachs Buy $191.00 2 days ago Matthew Harrison Morgan Stanley Buy $161.00 2 days ago Brian Skorney Robert W. Baird Buy $202.00 2 days ago Alethia Young Cantor Fitzgerald Buy $217.00 2 days ago Yun Zhong Janney Montgomery Buy $200.00 2 days ago Brian Abrahams RBC Capital Buy -- 3 days ago Martin Auster Credit Suisse Buy $189.00 3 days ago Tim Chiang BTIG Buy $190.00 13 days ago Source: tipranks ### Investment Suitability Like with all biotech companies in the discovery phase, SRPT is volatile and risky. Any FDA approval delays could disappoint markets, sending the stock lower. Clinical study costs could rise, but in Sarepta's case, the company has plenty of cash on hand. It is unlikely to need a cash raise through a share sale. * 7 Stocks to Buy That Are Run By Billionaires ### Bottom Line on SRPT Stock Sarepta Therapeutics stock benefited from the latest rebound in biotechnology stocks, but could move even higher in the longer term. It has a goal of commencing its confirmatory trial with commercial material this year. Given the strong team, doctors and scientists involved, chances are good that the trial, which has 24 patients, goes well and will bring positive results. As of this writing, Chris Lau did not hold a position in any of the aforementioned securities. ### More From InvestorPlace * 2 Toxic Pot Stocks You Should Avoid * 10 Stocks You Can Set and Forget (Even In This Market) * 10 Virtual Assistants for the Future of Smart Homes * 7 5G Stocks to Buy as the Race for Spectrum Tightens Compare Brokers The post Why Sarepta Therapeutics Stock Is Starting to Shine Again appeared first on InvestorPlace.

  • CNBC6 days ago

    Bear market in value stocks is ending, Wells Fargo predicts a 2019 comeback

    Wells Fargo's Christopher Harvey expects value names to be the big winners in the second half of 2019.

  • CNBC9 days ago

    Two ways to play the biotech boom

    Biotech stocks are on fire after a string of deals in the space. Here are two ways investors could play the space.

  • CNBC9 days ago

    Biotech's breaking out, and here's why some market experts think an even bigger rally is ahead

    Biotech just saw a big rally, and market experts believe the sector could have more room to run.

  • Three Healthcare Stocks Rallying Over 10% Today
    Market Realist9 days ago

    Three Healthcare Stocks Rallying Over 10% Today

    Three Healthcare Stocks Rallying Over 10% Today ## Three healthcare stocks The broader market is trading in the green territory today but largely on a mixed note compared to the volatility in the previous couple of sessions. At 11:40 AM ET, the S&P 500 Index (SPY), NASDAQ Composite Index (QQQ), and Dow Jones Industrial Average were trading with 0.8%, 1.1%, and 0.6% gains. However, some healthcare stocks (XLV)(VHT)(IBB) were making huge moves today. Let’s take a look. ## Loxo Oncology Today before the market opened, the American pharmaceutical giant Eli Lilly and Company (LLY) announced the acquisition of Loxo Oncology (LOXO). According to the agreement between the two companies, Eli Lilly will acquire Loxo for $235.00 per share in cash, which translates into approximately $8.0 billion. After the news came out, Loxo stock surged nearly 66.0% to $232.12. ## Sage Therapeutics The biopharmaceutical firm Sage Therapeutics (SAGE) revealed positive results of the Phase 3 ROBIN Study today. The outcome of the study suggested a “significant improvement” in women with postpartum depression (or PPD) who were treated with its SAGE-217 drug for two weeks. This news boosted investors’ confidence, and SAGE stock surged 62.1% to a day high of $158.09. ## Exact Sciences The molecular diagnostics firm Exact Sciences (EXAS) said today that it expects its fourth quarter of 2018 revenue between $142.5 million and $143.5 million, which reflected about a 64% rise in its revenue from the fourth quarter of the previous year. In a press release, the company said that it “completed approximately 292,000 Cologuard tests during the fourth quarter of 2018,” up about 66% year-over-year. Plus, Exact Sciences noted, “Nearly 15,000 health care providers ordered Cologuard for the first time during the fourth quarter of 2018.” These positive developments drove EXAS stock to rally today to post a day high of $72.78, up 11.0% from its previous session’s closing price. Note that in 2018, LOXO, LLY, and EXAS rose 66.4%, 37.0%, and 20.1%, respectively, while SAGE fell 41.8%.

  • MarketWatch9 days ago

    Sage Therapeutics's stock shoots higher after postpartum depression treatment's positive trial results

    Shares of Sage Therapeutics Inc. shot up 44% in active early-afternoon trade, after the Massachusetts-based biopharmceutical company said its treatment for postpartum depression (PPD) met the primary and secondary endpoints of a phase 3 trial. Trading volume swelled to about 3 million shares, compared with the full-day average of about 463,000 shares. The company said patients treated with SAGE-217 30 milligrams had a "statistically significant improvement" in the Hamilton Rating Scale for depression when compared with placebo, and was generally well tolerated. Separately, the company said it will provide updates on key 2019 initiatives, including drug milestones expected in the next 12-to-18 months, when it is scheduled to present last Tuesday at the J.P. Morgan Healthcare Conference. The stock has still declined 17% over the past 12 months, while the iShares Nasdaq Biotechnology ETF has slipped 2.9% and the S&P 500 has lost 6.5%.

  • MarketWatch10 days ago

    Axsome's stock nearly triples on heavy volume after positive trial of depression treatment

    Shares of Axsome Therapeutics Inc. rocketed 164% in very active premarket trade Monday, after the biopharmaceutical company developing therapies to treat central nervous system disorders said a phase 2 trial of its AXS-05 met its primary endpoint, and "significantly improved symptoms of depression." Trading volume ballooned to about 1.5 million shares, already about 5-times the full-day average of about 306,000 shares, and enough to make the stock the most actively traded ahead of the open. The company said AXS-05 met the primary endpoint by demonstrating a "highly statistically significant reduction" in the Montgomery-Asberg Depression Rating Scale total score. The company said ASX-05 was also safe and well tolerated, with no serious adverse events. The stock had tumbled 28% over the past three months through Friday, while the iShares Nasdaq Biotechnology ETF had lost 12.0% and the S&P 500 had declined 12.3%.

  • MarketWatch12 days ago

    Insmed stock shoots up 18% after company says it expects drug Arikayce to bring in $9.8 million in fourth quarter

    Shares of Insmed Incorporated shot up 18% in after-hours trading Friday after the company announced it expected sales of its antibacterial Arikayce to be $9.8 million for the fourth quarter, with $9.2 million in U.S. sales and $600,000 in sales outside the U.S. The drug is used to treat patients with a lung disease caused by a group of bacteria called Mycobacterium avium complex (MAC) and who do not respond to traditional treatment. Arikayce was granted accelerated approval by the FDA in September. Insmed said more than 500 U.S. patients had started treatment with the drug and approximately 600 physicians had written at least one prescription for the therapy as of Dec. 31. Shares of Insmed have fallen 51% in the past 12 months, while the iShares NASDAQ Biotech ETF has fallen 6.75%. The S&P 500 has fallen 7%.

  • Bristol-Myers to Acquire Celgene: Healthcare ETFs in Focus
    Zacks13 days ago

    Bristol-Myers to Acquire Celgene: Healthcare ETFs in Focus

    The news has put the spotlight on a number of healthcare ETFs, especially biotech and pharma, which could be the best ways for investors to tap the opportunity arising from the BMY-CELG deal.

  • MarketWatch13 days ago

    Mersana to discontinue development of one cancer treatment to focus on another

    Biopharmaceutical company Mersana Therapeutics Inc. said Friday that it will discontinue development of its XMT-1522 cancer treatment, following a strategic evaluation by the company. The stock is currently halted for news. Instead, the company will focus its resources on advancing XMT-1536. XMT-1522 was being developed with its partner, Takeda Pharmaceutical Co. Ltd. . "We have made the difficult decision to terminate the further development of XMT-1522 despite a favorable emerging profile of efficacy and tolerability due to the competitive environment for HER2-targeted therapies," said Mersana Chief Executive Anna Protopapas. The company said it plans to report phase 1 trial dose escalation data in the first half of 2019. The stock has plunged 56% over the past three months, while the iShares Nasdaq Biotechnology ETF has lost 17% and the S&P 500 has shed 16%.

  • Benzinga17 days ago

    Attention Biotech Investors: Mark Your Calendar For These January PDUFA Dates

    After a strong 2017, biotech stocks are on track to end the year in the red despite a record 59 new molecular entity approvals , some noteworthy M&A deals and several breakthrough developments in drug ...

  • MarketWatch17 days ago

    Heron stock up 4.3% after opioid alternative granted priority review designation from FDA

    Shares of Heron Therapeutics rose 4.5% in premarket trade Monday after the company announced the U.S. Food and Drug Administration had accepted the new drug application for its non-opioid alternative for post-operative pain management, granting it priority review designation. The product, dubbed HTX-011, is a combination of a long-acting, extended-release form of local anesthetic bupivacaine and the anti-inflammatory medication meloxicam. "We believe that HTX-011 could have a considerable impact on the lives of patients by significantly reducing the proportion of patients who experience severe pain and receive opioids after surgery, especially at discharge," said Heron Chief Executive Barry D. Quart in a statement. The FDA had previously granted breakthrough therapy status for HTX-011 based on the results of Phase 2 studies and two completed Phase 3 studies. Those studies showed the drug produced significant reductions in pain intensity and need for opioids compared to a placebo and bupivacaine alone. Shares of Heron have gained 31% this year, while shares of the iShares NASDAQ Biotechnology ETF have fallen 11%. The S&P 500 has fallen 7%.

  • Benzinga17 days ago

    The Week Ahead In Biotech: Conferences, PDUFA Dates And Clinical Trials

    After extended weakness, biotech stocks turned a corner along with the broader markets to close out the week. With just a session left, it looks less likely the sector ends in the black for the year. The ...

  • Benzinga21 days ago

    6 Valuable Pipeline Drugs With Upcoming Catalysts

    Heading into December, biotech stocks held up fairly well in 2018. Evaluate Pharma , a firm specializing in data-driven news and analysis in biotech, compiled a list of blockbuster drugs in the works with ...

  • Mirati Therapeutics Added To NASDAQ Biotechnology Index
    PR Newswire27 days ago

    Mirati Therapeutics Added To NASDAQ Biotechnology Index

    SAN DIEGO , Dec. 20, 2018 /PRNewswire/ -- Mirati Therapeutics, Inc. (NASDAQ: MRTX), a clinical-stage targeted oncology company, today announced that it has been selected for addition to the NASDAQ Biotechnology ...

  • Is iShares NASDAQ Biotechnology Index (ETF) (IBB) A Good Stock To Buy?
    Insider Monkey29 days ago

    Is iShares NASDAQ Biotechnology Index (ETF) (IBB) A Good Stock To Buy?

    You probably know from experience that there is not as much information on small-cap companies as there is on large companies. Of course, this makes it really hard and difficult for individual investors to make proper and accurate analysis of certain small-cap companies. However, well-known and successful hedge fund investors like Carl Icahn and George […]

  • InvestorPlacelast month

    Best ETFs of 2019: Financial Select Sector SPDR Fund Will Rise Again

    You’ll find them in the Financial Select Sector SPDR Fund (NYSEARCA:XLF). It’s Berkshire Hathaway (NYSE:BRK.A, NYSE:BRK.B), which represents over 13% of assets. The best-known Berkshire insurance holding is Geico, which serves consumers, but they’re also heavily involved in business reinsurance, commercial property insurance and worker’s compensation.

  • Market Exclusivelast month

    Market Morning: Rate Hike Ahead, Obamacare Struck Down, JNJ Asbestos Scandal, Qatar Challenges Saudis

    Economic Data Ahead This week we have a few interesting pieces of data on the economic docket. Monday, not much happening but foreign buying of T-bonds could make a bit of a splash. The yield curve has inverted, partially, on the short end of Treasury maturities, and has flattened out on the longer end, and […] The post Market Morning: Rate Hike Ahead, Obamacare Struck Down, JNJ Asbestos Scandal, Qatar Challenges Saudis appeared first on Market Exclusive.

  • The Zacks Analyst Blog Highlights: Gilead Sciences, Alexion Pharmaceuticals, Regeneron Pharmaceutical and Biogen
    Zackslast month

    The Zacks Analyst Blog Highlights: Gilead Sciences, Alexion Pharmaceuticals, Regeneron Pharmaceutical and Biogen

    The Zacks Analyst Blog Highlights: Gilead Sciences, Alexion Pharmaceuticals, Regeneron Pharmaceutical and Biogen

  • ETF Edge, January 7, 2019
    CNBC Videos9 days ago

    ETF Edge, January 7, 2019

    A biotech breakout. The Apple effect. And do ETFs really cause volatility? With CNBC's Bob Pisani, Dave Nadig, ETF.com and Doug Yones, New York Stock Exchange.

  • ETF Edge: Biotech breakout
    CNBC Videos9 days ago

    ETF Edge: Biotech breakout

    Biotech ETFs are soaring today as deal talk in the space heats up. The XBI is up 5 percent and the IBB is up 3 percent. We look under the hood of these two big biotech ETFs and discuss the differences.