ORTX - Orchard Therapeutics plc

NasdaqGS - NasdaqGS Real Time Price. Currency in USD
17.30
+0.25 (+1.47%)
As of 1:50PM EDT. Market open.
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Previous Close17.05
Open17.06
Bid17.18 x 1300
Ask17.30 x 1400
Day's Range17.06 - 17.66
52 Week Range8.65 - 21.64
Volume55,259
Avg. Volume104,601
Market Cap1.486B
Beta (3Y Monthly)N/A
PE Ratio (TTM)N/A
EPS (TTM)-10.22
Earnings DateN/A
Forward Dividend & YieldN/A (N/A)
Ex-Dividend DateN/A
1y Target Est24.33
Trade prices are not sourced from all markets
  • GlobeNewswire7 hours ago

    Orchard Therapeutics Announces First Patient Dosed with Cryopreserved Formulation of OTL-103 Gene Therapy for the Treatment of Wiskott-Aldrich Syndrome

    BOSTON and LONDON, April 25, 2019 (GLOBE NEWSWIRE) -- Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced that the first patient with Wiskott-Aldrich Syndrome (WAS) has been dosed in a open label study designed to evaluate engraftment of the cryopreserved formulation of OTL-103, its ex vivo autologous hematopoietic stem cell (HSC) gene therapy. “We are excited to have reached this milestone with the infusion of cryopreserved gene-modified stem cells in a patient with Wiskott-Aldrich Syndrome, a life-threatening immune disorder for which there is no available therapy outside of allogeneic stem cell transplantation, which carries a significant risk of morbidity and mortality,” said Mark Rothera, president and chief executive officer of Orchard.

  • GlobeNewswire10 days ago

    Orchard Therapeutics Announces Presentation of Clinical Proof-of-Concept for OTL-300 for the Treatment of Transfusion-Dependent Beta-Thalassemia at the 22nd American Society of Gene & Cell Therapy Annual Meeting

    Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced the achievement of clinical proof-of-concept based on data from the trial of its ex vivo, autologous, hematopoietic stem cell (HSC) gene therapy, OTL-300, for the treatment of transfusion-dependent beta-thalassemia (TDT). The data will be published online today in an abstract via the American Society of Gene & Cell Therapy (ASGCT) website, and the full data set will be featured in an oral presentation at the 22nd ASGCT Annual Meeting to be held on April 29 – May 2, 2019 in Washington, D.C. Specifically, the presentation will report the updated safety and efficacy results of OTL-300 in nine transfusion-dependent severe phenotype TDT patients (six pediatric, three adult), including β0/β0 genotype, with minimum one year post-treatment follow up, as well as details on engraftment of gene-modified cells and vector integration site analyses.

  • Will Orchard Therapeutics Continue to Surge Higher?
    Zacks29 days ago

    Will Orchard Therapeutics Continue to Surge Higher?

    As of late, it has definitely been a great time to be an investor in Orchard Therapeutics.

  • GlobeNewswire29 days ago

    Orchard Therapeutics Presents New Registrational Data Demonstrating Sustained Clinical Benefit of OTL-200 for the Treatment of MLD

    Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, presented the full registrational dataset from a 20 patient trial evaluating the efficacy and safety of OTL-200, an ex vivo autologous hematopoietic stem cell-based (HSC) gene therapy for the treatment of metachromatic leukodystrophy (MLD). The data, which included updated results on the two-year primary endpoints, in addition to new follow-up data at three years, were featured yesterday in an oral presentation at the 45th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT).

  • GlobeNewswirelast month

    Orchard Therapeutics Reports 2018 Financial Results and Reviews Recent Business Highlights

    Three Lead Programs for MLD, ADA-SCID and WAS on Track for Regulatory Filings Over the Next Three Years, with MLD and ADA-SCID Expected in 2020 Registrational Data Showing 100%.

  • GlobeNewswirelast month

    Orchard Therapeutics Strengthens Global Manufacturing and Supply Chain Leadership with Appointment of Ran Zheng as Chief Technical Officer

    Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced the appointment of Ran Zheng to the newly created position of chief technical officer. Upon joining Orchard, Ms. Zheng will oversee multiple related functions, including process development, manufacturing, quality, facilities and engineering, supply chain, and CMC program management. Ms. Zheng, who brings more than 20 years of experience in technical operations, will report to Mark Rothera, president and chief executive officer of Orchard, and serve as a member of the executive leadership team.

  • What Kind Of Shareholders Own Orchard Therapeutics plc (NASDAQ:ORTX)?
    Simply Wall St.last month

    What Kind Of Shareholders Own Orchard Therapeutics plc (NASDAQ:ORTX)?

    The big shareholder groups in Orchard Therapeutics plc (NASDAQ:ORTX) have power over the company. Generally speaking, as a company grows, institutions will increase their ownership. Conversely, insiders often decrease theirRead More...

  • GlobeNewswirelast month

    Orchard Therapeutics to Webcast Conference Call of 2018 Financial Results on March 21, 2019

    BOSTON and LONDON, March 14, 2019 -- Orchard Therapeutics (NASDAQ: ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients.

  • GlobeNewswirelast month

    Orchard Therapeutics Announces Acceptance of OTL-200 Abstract for MLD at the 45th Annual Meeting of the European Society for Blood and Bone Marrow Transplantation (EBMT)

    Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced that new clinical data from the registrational trial of OTL-200 in metachromatic leukodystrophy (MLD) will be featured in an oral presentation at the 45th Annual Meeting of the European Society for Blood and Bone Marrow Transplantation (EBMT) to be held on March 24-27, 2019 in Frankfurt, Germany. The presentation will feature updated safety and efficacy results from patients with a minimum of three years of follow-up following treatment with gene therapy.

  • GlobeNewswire2 months ago

    Orchard Therapeutics to Present at the Cowen 39th Annual Health Care Conference on March 11, 2019

    BOSTON and LONDON, March 04, 2019 -- Orchard Therapeutics (NASDAQ: ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients.

  • GlobeNewswire2 months ago

    Orchard Therapeutics Presents Clinical Proof-of-Concept Data for OTL-102 for the Treatment of X-CGD

    BOSTON and LONDON, Feb. 25, 2019 (GLOBE NEWSWIRE) -- Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, yesterday presented additional clinical proof-of-concept data evaluating OTL-102, an ex vivo, autologous, hematopoietic stem cell based gene therapy for the treatment of X-linked chronic granulomatous disease (X-CGD) during an oral presentation at the 2019 Transplantation and Cellular Therapy Meetings of ASBMT and CIBMTR in Houston, TX. The proof-of-concept data was first presented during the Presidential Symposium at the American Society of Hematology (ASH) Annual Meeting & Exposition in December 2018.

  • GlobeNewswire2 months ago

    Orchard Therapeutics Presents Two-Year Follow-Up Data Versus Historical Control from Registrational Trial of OTL-101 for the Treatment of ADA-SCID

    100% Overall Survival and 100% Event Free Survival in Patients Treated with OTL-101 Compared to 88% OS and 56% EvFS with Historical HSCT Overall at 24 months Biologics License.

  • GlobeNewswire3 months ago

    Orchard Therapeutics Announces Acceptance of Late-Breaking Abstracts of OTL-101 for ADA-SCID and OTL-102 for X-CGD at the 2019 Transplantation and Cellular Therapy Meetings of ASBMT and CIBMTR

    BOSTON and LONDON, Feb. 06, 2019 -- Orchard Therapeutics (NASDAQ: ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients.

  • GlobeNewswire3 months ago

    Orchard Announces Publication by San Raffaele-Telethon Institute for Gene Therapy of OTL-300 Clinical Data for the Treatment of Transfusion-Dependent Beta-Thalassemia in Nature Medicine

    Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced that the San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget) has published encouraging results from a clinical trial of OTL-300, an autologous ex vivo lentiviral gene therapy program being studied in individuals with transfusion-dependent beta-thalassemia. “Orchard recognizes the pioneering work of researchers and clinicians from SR-Tiget that has led to this peer-reviewed publication of promising clinical data for the treatment of transfusion-dependent beta-thalassemia patients in Nature Medicine,” said Andrea Spezzi, M.D., chief medical officer of Orchard Therapeutics.

  • GlobeNewswire4 months ago

    Orchard Therapeutics Highlights Recent Accomplishments and 2019 Strategic Priorities as a Global Leader in Gene Therapy

    BOSTON and LONDON, Jan. 07, 2019 (GLOBE NEWSWIRE) -- Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today summarized recent accomplishments and 2019 strategic priorities in conjunction with its attendance at the 37th Annual J.P. Morgan Healthcare Conference in San Francisco. Mark Rothera, president and chief executive officer, will present a business overview outlining the company’s progress as a global leader in gene therapy on Wednesday, January 9, 2019 at 3:00 p.m. PT that will be webcast at ir.orchard-tx.com. “2018 was a momentous year for Orchard, marked by the success of our acquisition and integration of GSK’s rare disease ex-vivo gene therapy portfolio, initial scaling of our manufacturing capabilities and completion of our initial public offering,” said Mr. Rothera.

  • GlobeNewswire4 months ago

    Orchard Therapeutics to Present at the 37th Annual J.P. Morgan Healthcare Conference on January 9, 2019

    BOSTON and LONDON, Jan. 02, 2019 -- Orchard Therapeutics (NASDAQ: ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients.

  • 2019 biotech preview: Money is pouring into the Bay Area and so is Big Pharma
    American City Business Journals4 months ago

    2019 biotech preview: Money is pouring into the Bay Area and so is Big Pharma

    Person to watch Jennifer Cook The 25-year Genentech veteran — most recently in charge of clinical operations — after a year on the job is leading early cancer diagnostics company Grail toward a potential $500 million IPO. Grail is also launching a 50,000-person study to see if its technology can detect multiple cancer types earlier, particularly lung cancer. Technology to watch AI / ML From Daphne Koller’s Insitro to Alice Zhang’s Verge Genomics Inc., artificial intelligence and machine learning are moving beyond hype to real-time lab use.

  • Benzinga4 months ago

    Positive Data From Orchard Therapeutics Turns Goldman Sachs Bullish

    Orchard Therapeutics PLC – ADR (NASDAQ: ORTX ), a rare disease gene therapy company, recently went public, offering 14.29 million shares at $14 each. The shares were listed on the Nasdaq Oct. 31 and ended ...

  • Targeting 'bubble baby' disease, this gene therapy company is planting a flag in the East Bay
    American City Business Journals4 months ago

    Targeting 'bubble baby' disease, this gene therapy company is planting a flag in the East Bay

    Orchard Therapeutics is tackling "bubble baby" disease and other rare genetic conditions with gene therapy.

  • GlobeNewswire4 months ago

    Orchard Therapeutics Announces the Build-out of New Gene Therapy Manufacturing Facility in California

    Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced that it has signed a long-term lease agreement to build-out a gene therapy manufacturing facility in Fremont, California. The new 150,000-square-foot facility significantly increases Orchard’s California footprint and adds to the Foster City and Menlo Park, California sites, which oversee the ongoing development and validation of the manufacture of Orchard’s ex vivo gene therapy product candidates.

  • GlobeNewswire5 months ago

    Orchard Therapeutics Appoints Industry Veteran Alicia Secor to its Board of Directors

    BOSTON and LONDON, Dec. 07, 2018 (GLOBE NEWSWIRE) -- Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced the appointment of Alicia Secor to its board of directors. Ms. Secor brings more than 25 years of life sciences leadership and commercial product expertise with a particular focus in rare disease and other areas of unmet need, most recently serving as president and chief executive officer at Juniper Pharmaceuticals, Inc.

  • GlobeNewswire5 months ago

    Donald B. Kohn, MD, Orchard Therapeutics Scientific Advisory Board Member, Presents Clinical Proof-of-Concept Data for OTL-102 Gene Therapy for the Treatment of Patients with X-CGD at the Presidential Symposium at the 2018 ASH Annual Meeting

    BOSTON and LONDON, Dec. 05, 2018 (GLOBE NEWSWIRE) -- Orchard Therapeutics (ORTX), a leading commercial-stage biopharmaceutical company dedicated to transforming the lives of patients with serious and life-threatening rare diseases through innovative gene therapies, today announced that Scientific Advisory Board Member, Donald B. Kohn, MD, presented clinical proof-of-concept data from an ongoing academic clinical trial evaluating OTL-102 for the treatment of X-Linked Chronic Granulomatous Disease (X-CGD) during the Presidential Symposium at the 2018 American Society of Hematology (ASH) Annual Meeting & Exposition on December 4, 2018. X-CGD is a life-threatening inherited immunodeficiency disorder which is caused by a genetic mutation that results in the inability of neutrophils to effectively kill bacterial and fungal pathogens.

  • GlobeNewswire6 months ago

    Orchard Therapeutics Strengthens Global Commercial Leadership Team with Appointments of Heads of US and EMEA Region Commercial Operations

    Commercial team preparing for potential gene therapy launches BOSTON and LONDON, Nov. 08, 2018 -- Orchard Therapeutics, a leading commercial-stage biotech company.

  • GlobeNewswire6 months ago

    Orchard Therapeutics Announces Closing of $225 Million Initial Public Offering, Including the Partial Exercise of Underwriters’ Option

    BOSTON and LONDON, Nov. 05, 2018 -- Orchard Therapeutics plc (Nasdaq: ORTX), a biopharmaceutical company dedicated to transforming the lives of patients with serious and.