Previous Close | 0.4200 |
Open | 0.4200 |
Bid | 0.4000 x N/A |
Ask | 0.4150 x N/A |
Day's Range | 0.4200 - 0.4200 |
52 Week Range | 0.0650 - 0.6900 |
Volume | 500 |
Avg. Volume | 143,885 |
Market Cap | 92M |
Beta (5Y Monthly) | 0.31 |
PE Ratio (TTM) | N/A |
EPS (TTM) | -0.0210 |
Earnings Date | N/A |
Forward Dividend & Yield | N/A (N/A) |
Ex-Dividend Date | 2006-12-27 |
1y Target Est | 0.73 |
In anticipation of a clinical study in Q2 of 2020, Sirona has completed the first required toxicity study for the increased dose (0.4%) of TFC-1067. TFC-1067 .4% was found to be a non-irritant in 100% of subjects in the patch test. In a similar study1 (published in the Annals of Dermatology 2017), 20 volunteers were patch-tested with varying levels of hydroquinone (HQ) alone and in combination with retinoic acid (RA).
In anticipation of a clinical study in Q2 of 2020, Sirona has completed the first required toxicity study for the increased dose (0.4%) of TFC-1067. TFC-1067 .4% was found to be a non-irritant in 100% of subjects in the patch test. In a similar study1 (published in the Annals of Dermatology 2017), 20 volunteers were patch-tested with varying levels of hydroquinone (HQ) alone and in combination with retinoic acid (RA).
Sirona's scientific team at TFChem and the Senior Toxicologist at CEHTRA (www.cehtra.com) have reviewed recent in-vitro safety assays and verified that the compound can be tested at double the prior concentration. The Human Patch Test for cutaneous irritation will be conducted under physician supervision at Cosmepar (www.cosmepar.fr/en/) in France . Cosmepar's specialized services include evaluating the tolerance of cosmetic products.
Sirona's scientific team at TFChem and the Senior Toxicologist at CEHTRA (www.cehtra.com) have reviewed recent in-vitro safety assays and verified that the compound can be tested at double the prior concentration. The Human Patch Test for cutaneous irritation will be conducted under physician supervision at Cosmepar (www.cosmepar.fr/en/) in France . Cosmepar's specialized services include evaluating the tolerance of cosmetic products.
Mr. Pinqiao Zhao is a university-trained chemist who has extensive experience with fluorination chemistry and manufacturing. Mr. Zhao has participated in multiple publications and is an accomplished innovator in chemical manufacturing.
Mr. Pinqiao Zhao is a university-trained chemist who has extensive experience with fluorination chemistry and manufacturing. Mr. Zhao has participated in multiple publications and is an accomplished innovator in chemical manufacturing.
Rodan + Fields, the leading skin care brand in the United States 1, is preparing to incorporate novel ingredient TFC-1067 into their product lines. Backed by extensive scientific research, TFC-1067 is clinically proven to be safe and effective at reducing the visibility of dark spots, brightening and evening skin tone. Chief Scientific Officer, Dr. Geraldine Deliencourt-Godefroy , will introduce TFChem, the wholly owned French subsidiary of Sirona Biochem, which has created breakthrough skin care solutions using platform-based technology.
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Tinyi will have distribution rights within Asia as well as exclusive rights for China . Tinyi, founded in 2006, is a well-established cosmetic ingredient distributor headquartered in Guangzhou , the cosmetic valley in China .
Tinyi will have distribution rights within Asia as well as exclusive rights for China . Tinyi, founded in 2006, is a well-established cosmetic ingredient distributor headquartered in Guangzhou , the cosmetic valley in China .
Since 2015, Cosmetic 360 has become an exclusive international event that allows the most influential cosmetic companies and industry decision makers to access the latest advancements in science. Dr. Deliencourt-Godefroy will be joined by lab colleague Dr. Jocelyne Legoedec as well as Ms. Michelle Seltenrich , Vice President Operations, to present the most recent advancements of Sirona's novel skin lightener, TFC-1067. Thanks to compelling clinical evidence of superiority to selectively remove dark spots in comparison to a leading brand containing hydroquinone, previous challenges to partnering have been overcome and Sirona is now well positioned with TFC-1067.
Since 2015, Cosmetic 360 has become an exclusive international event that allows the most influential cosmetic companies and industry decision makers to access the latest advancements in science. Dr. Deliencourt-Godefroy will be joined by lab colleague Dr. Jocelyne Legoedec as well as Ms. Michelle Seltenrich , Vice President Operations, to present the most recent advancements of Sirona's novel skin lightener, TFC-1067. Thanks to compelling clinical evidence of superiority to selectively remove dark spots in comparison to a leading brand containing hydroquinone, previous challenges to partnering have been overcome and Sirona is now well positioned with TFC-1067.
Rodan and Fields will be the first to market for a consumer product utilizing TFC-1067 in certain countries including United States . Under the terms of the agreement, Sirona will receive an upfront and milestone payments as well as on-going revenue in return for the manufacture and supply of TFC-1067, a novel, new skin brightening ingredient, for use by Rodan + Fields on a non-exclusive basis and Rodan + Fields will launch a new product incorporating the ingredient. Further details of this agreement will remain confidential for strategic reasons.
Rodan and Fields will be the first to market for a consumer product utilizing TFC-1067 in certain countries including United States . Under the terms of the agreement, Sirona will receive an upfront and milestone payments as well as on-going revenue in return for the manufacture and supply of TFC-1067, a novel, new skin brightening ingredient, for use by Rodan + Fields on a non-exclusive basis and Rodan + Fields will launch a new product incorporating the ingredient. Further details of this agreement will remain confidential for strategic reasons.
The Rights Plan is subject to acceptance by the TSX Venture Exchange ("TSXV") and ratification by Sirona's shareholders within six months. If the shareholders do not ratify the Rights Plan at the AGM, the Rights Plan and all the rights outstanding at the time will terminate.
The Private Placement consists of 3,750,000 units, (the "Units") at a price of $0.40 per Unit. Each Unit consists of one common share and one transferable share purchase warrant, each whole warrant exercisable into one additional common share of the Company for a period of 3 years from the date of issue at a price of $0.60 per share subject to an acceleration clause. All securities issued under the Private Placement are subject to statutory hold periods expiring on November 10, 2019 . Proceeds will be used to establish Asia -based manufacturing for TFC-1067 as well as to accelerate Sirona's anti-ageing and anti-wrinkle projects.
The private placement consists of 2,500,000 units, (the "Units") at a price of $0.40 per Unit. Each Unit consists of one common share and one transferable share purchase warrant, each whole warrant exercisable into one additional common share of the Company for a period of 3 years from the date of issue at a price of $0.60 per share subject to an acceleration clause. The Company is proposing to pay a finder's fee to an agent or agents that assist in procuring the proceeds of the offering. Such Fee shall consist of a cash fee equal to no more than 8% of the total proceeds of the Private Placement placed by such finder and warrants up to 8% of the number of Units the finder sells in the Private Placement (the "Finder's Warrants").
VANCOUVER , July 4, 2019 /CNW/ - Sirona Biochem Corp. (SBM.V) (ZSB.F) ("Sirona") is pleased to provide a corporate update from the Company's CEO, Dr. Howard Verrico , regarding its plans both near and long term in the following Q&A format. Why are the details limited on the clinical trial update from Wanbang?
VANCOUVER , July 4, 2019 /CNW/ - Sirona Biochem Corp. (SBM.V) (ZSB.F) ("Sirona") is pleased to provide a corporate update from the Company's CEO, Dr. Howard Verrico , regarding its plans both near and long term in the following Q&A format. Why are the details limited on the clinical trial update from Wanbang?
Wanbang and Sirona are unable to comment further on the details of the progress for strategic as well as competitive reasons. Sirona Biochem's SGLT2 inhibitor, TFC-039, was licensed to Wanbang Biopharmaceuticals, a wholly owned subsidiary of Shanghai Fosun Pharmaceutical Group in 2014 with exclusive rights for China . In exchange for this license, Wanbang Biopharma will provide upfront and milestone payments of up to US$9.5M in addition to royalty payments for product sales in China .
Wanbang and Sirona are unable to comment further on the details of the progress for strategic as well as competitive reasons. Sirona Biochem's SGLT2 inhibitor, TFC-039, was licensed to Wanbang Biopharmaceuticals, a wholly owned subsidiary of Shanghai Fosun Pharmaceutical Group in 2014 with exclusive rights for China . In exchange for this license, Wanbang Biopharma will provide upfront and milestone payments of up to US$9.5M in addition to royalty payments for product sales in China .
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The total number of shares represented by shareholders present in person and by proxy at the meeting was 32,141,666 million representing 15.47% of Sirona's issued and outstanding Common Shares. All of the matters put forward before shareholders for consideration and approval as set out in the Company's Management Information Circular dated 22nd of May, 2019, were approved by the requisite majority of votes cast at the Meeting.
This term sheet covers all material terms and conditions of a definitive agreement with San Francisco -based, industry leading, Rodan + Fields. The definitive agreement is expected to be signed in Q3/2019. The term sheet stipulates Sirona will become a manufacturer and supplier of TFC-1067 for use by Rodan + Fields on a non-exclusive basis in its current markets ( USA , Canada and Australia ) as well as future regions.