10x Genomics Commercially Launches Visium HD Spatial Gene Expression Assay

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Began global shipments for Visium HD, a new product that enables whole transcriptome spatial discovery at single cell–scale resolution 

PLEASANTON, Calif., March 26, 2024 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, announced today the commercial availability of its Visium HD Spatial Gene Expression product. This assay enables researchers to measure the whole transcriptome from FFPE tissue sections at single cell-scale resolution.

A side-by-side comparison of Visium data (left) and Visium HD data (right) in FFPE human colorectal cancer, demonstrating the discovery power of whole transcriptome spatial gene expression at single cell–scale resolution.
A side-by-side comparison of Visium data (left) and Visium HD data (right) in FFPE human colorectal cancer, demonstrating the discovery power of whole transcriptome spatial gene expression at single cell–scale resolution.

"Visium HD is a game-changer for spatial discovery research, and our team couldn't be more proud and excited to get this long-awaited product into the hands of our customers," said Michael Schnall-Levin, Founding Scientist and Chief Technology Officer at 10x Genomics. "This is the most requested product in our history, and I can't think of a better example of how 10x listens to our customers and takes on the hardest development challenges to have the biggest impact on scientific research. We're confident researchers will agree Visium HD was well worth the wait."

Combining the power of whole transcriptome spatial discovery with histological insights, Visium HD enables comprehensive characterization of FFPE tissue samples. Visium HD offers:

  • Whole transcriptome spatial discovery power at single cell scale: Use next-generation slide architecture, which provides transcript data in 2 x 2 µm barcoded squares without gaps, to resolve fine anatomical structures and map cell types and states at single cell-scale resolution.

  • Best-in-class sequencing-based spatial transcriptomics data: Map gene expression with precision and high confidence using a simple and robust workflow exclusively available on Visium CytAssist.

  • FFPE compatibility: Generate powerful data from human or mouse FFPE samples, including archived blocks or pre-sectioned slides, using a universal sample preparation protocol.

  • Enhanced histology: Integrate H&E or IF images with high-resolution spatial transcriptomics from the same tissue section.

  • Easy-to-use analysis and visualization tools: Seamlessly combine histological and gene expression data using updated versions of Space Ranger and Loupe Browser to enable intuitive data exploration and accelerate discovery.

The company will host a webinar to introduce Visium HD on April 2, 2024 at 12 PM E.T. Register here.

About 10x Genomics
10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter).

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Disclosure Information
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Contacts
Investors: investors@10xgenomics.com
Media: media@10xgenomics.com

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SOURCE 10x Genomics, Inc

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