Celanese (CE) and Secarna Partner for Antisense Therapies
Celanese Corporation CE and Secarna Pharmaceuticals GmbH & Co. KG recently established a research collaboration to create long-acting implants delivering antisense oligonucleotides ("ASO").
ASOs are synthetic compounds that target specific messenger RNA to block the creation of proteins involved in the progression of a variety of diseases, including cardiometabolic, central nervous system, oncologic and uncommon disorders. Antisense therapy is a novel, commercially validated therapeutic method. However, it generally necessitates frequent administration or large dosages to ensure uptake at the desired site of action, resulting in a substantial treatment burden for patients.
The Celanese VitalDose Drug Delivery Platform and Secarna's proprietary ASO Drug Discovery and Development Platform will be used to create ASO-eluting implants with the potential to reduce dosing frequency, reduce off-target immune responses and improve targeting to provide better patient outcomes for a variety of indications.
The VitalDose medication Delivery Platform has a long history of usage in approved parenteral drugs in the United States and Europe, and it delivers consistent, controlled-release results. It can be programmed to deliver months to years of medication release and has shown consistent ASO release over a year.
Celanese's collaboration with Secarna, a prominent independent European antisense drug discovery and development company, enables the development of a novel implant with the potential to significantly alter how disease-modifying ASO treatments are given.
Shares of Celanese have gained 69.1% over the past year compared with a 32.6% rise of its industry.
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Celanese, on its fourth-quarter call, said that it expects adjusted earnings of $1.75-$2.00 per share for the first quarter of 2024. The company anticipates a significant rise in earnings per share year over year in 2024 due to M&M synergy capture, Clear Lake acetic acid and methanol expansions, lower interest expenses from deleveraging and lower inventory costs.
Celanese Corporation Price and Consensus
Celanese Corporation price-consensus-chart | Celanese Corporation Quote
Zacks Rank & Key Picks
Celanese currently carries a Zacks Rank #3 (Hold).
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Carpenter Technology currently carries a Zacks Rank #1. CRS beat the Zacks Consensus Estimate in three of the last four quarters while matching it once, with the average earnings surprise being 12.2%. The company’s shares have soared 71.1% in the past year.
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