MediciNova Posts Promising Data From COVID-19 Treatment Candidate

In this article:
  • MediciNova Inc (NASDAQ: MNOV) says the Phase 2 trial of MN-166 (ibudilast) in hospitalized COVID-19 patients demonstrated significant improvements compared to placebo for all four clinical endpoints analyzed.

  • The trial achieved statistical significance for one of the co-primary endpoints, the proportion of subjects free of respiratory failure.

  • The trial also achieved statistical significance for the proportion of subjects discharged from the hospital.

  • Related: MediciNova's Alcohol Use Disorder Candidate Reduces Alcohol Craving, Odds Of Heavy Drinking.

  • 71% of subjects in the MN-166 group and 35% of subjects in the placebo group were free of respiratory failure at Day 7.

  • 71% of subjects in the MN-166 group and 47% of subjects in the placebo group had improved clinical status.

  • 65% of subjects in the ibudilast group and 29% of subjects in the placebo group were discharged from the hospital.

  • There were two deaths in the placebo group and no deaths in the MN-166 (ibudilast) group.

  • There were no serious adverse events related to ibudilast.

  • Price Action: MNOV shares are up 8.09% at $2.54 during the premarket session on the last check Wednesday.

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