Moleculin Reveals Final Topline Data From European Study Of Annamycin In Leukemia Setting

Vandana Singh
1 min read
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In this article:

  • Moleculin Biotech Inc (NASDAQ: MBRX) announced the topline results from its MB-105 European Phase 1 clinical trial assessing the safety and efficacy of Annamycin as a single agent for relapsed or refractory acute myeloid leukemia (AML).

  • The final MB-105 results align with the overall safety profile of Annamycin and observations made in previously completed and ongoing clinical studies evaluating Annamycin.

  • Additionally, in the last cohort, where all subjects were at least 60 years of age, Annamycin demonstrated an overall response rate (ORR) of 80%.

  • Related: Moleculin Biotech's Annamycin In Leukemia Study Shows 80% Overall Response Rate.

  • "We also are encouraged by the absence of cardiotoxicity with Annamycin to date," said Chairman and CEO Walter Klemp.

  • "This is particularly relevant in light of a recently published retrospective study showing that the incidence of heart failure more than doubles for cancer patients treated with anthracyclines compared to cancer patients not receiving anthracyclines," Klemp added.

  • Topline results showed one CRi (complete response with incomplete recovery of peripheral blood count) and three PRs (Partial Response) for an 80% overall response rate (ORR) in the last cohort of elderly patients.

  • Price Action: MBRX shares are up 0.44% at $1.18 on the last check Monday

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This article Moleculin Reveals Final Topline Data From European Study Of Annamycin In Leukemia Setting originally appeared on Benzinga.com

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