Science 37 Holdings, Inc. (NASDAQ:SNCE) Q4 2022 Earnings Call Transcript
Science 37 Holdings, Inc. (NASDAQ:SNCE) Q4 2022 Earnings Call Transcript March 6, 2023
Operator: Greetings. Welcome to the Science 37 fourth quarter and full year 2022 earnings conference call. At this time, all participants are in listen-only mode. A question and answer session will follow the formal presentation. If anyone should require Operator assistance during the conference, please press star, zero from your telephone keypad. Please note that this conference is being recorded. I will now turn the conference over to Steven Halper with LifeSci Advisors. Steven, you may now begin.
Steven Halper: Thank you Rob, and thank you all for participating in today's call. Joining me are David Coman, Chief Executive Officer, and Mike Zaranek, Chief Financial Officer. Earlier today, Science 37 released financial results for the quarter ended December 31, 2022. A copy of the press release is available on the company's website. Before we begin, I'd like to remind you that management will make statements during this call that include forward-looking statements within the meaning of federal securities laws which are made pursuant to the Safe Harbor provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based upon our current estimates of various assumptions and involve material risks and uncertainties that could cause actual results or events to materially differ from those anticipated or implied by these forward-looking statements.
We encourage you to review our filings made with the Securities and Exchange Commission for a discussion of these risk factors, including in the Risk Factors section of the company's most recently filed periodic reports on Form 10-K and Form 10-Q and subsequent filings. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of today, and the company disclaims any obligation to update such statements for new information. We believe that certain non-GAAP metrics are useful in evaluating our operational performance. We use these non-GAAP measures to evaluate our ongoing operations and for internal planning and forecasting purposes. Information about non-GAAP financial measures referenced, including a reconciliation of those measures to the most comparable GAAP measures can be found in our SEC filings and in earnings materials available on the Investor Relations portion of our website at investors.science37.com.
I would now like to turn the call over to David Coman. David?
David Coman: Thanks Steve. Good morning everyone and thank you for joining us. We are pleased to report fourth quarter results that exceeded our most recent guidance and represent significant improvements quarter-over-quarter. Fourth quarter revenue was $15.9 million, finishing the year at $70.1 million, which was ahead of our expectations. Fourth quarter adjusted EBITDA was also ahead of expectations and marked an improvement of more than 20% quarter-over-quarter from negative $14.6 million to negative $11.6 million, finishing the year at negative $62.5 million. We also saw a healthy rebound in bookings in the fourth quarter with gross bookings of $33 million, which included a sizeable new project win from a repeat customer.
Our net bookings in the fourth quarter were just under $19 million, which includes the impact from the large scope reduction that we discussed on the third quarter call. As we look forward to 2023, given the previously reported industry challenges including longer decision making time, more cost consciousness and drug funding challenges, the 2022 booking shortfall, particularly in the third quarter, and project cancellations that we reported throughout the year, we are providing 2023 revenue guidance of $55 million to $60 million for the year. In response to these challenges, I'd like to take a few moments to highlight the steps we've taken to increase revenue growth and execute on our path to profitability. With the addition of our new Chief Commercial Officer, Michael Shipton, who joined us late in the third quarter, we're starting to gain measured optimism for top line growth acceleration.
As you may have seen in our recent website update, we have prioritized our Metasite offering as it is the greatest area of customer demand and provides us with the greatest differentiation for our company. Michael has also hired a new head of inside sales and growth accounts to generate additional demand amongst new customers, in addition to a head of real world evidence to promote the unique value of our Metasite for long term follow-up. He also expanded our CRO network with the most recent addition of Wuxi from China and is deepening our relationships in our strategic accounts. We believe all these additions will generate a material return to bookings growth as we progress throughout 2023. We are excited about the continued maturation of our technology infrastructure at the hands of our Chief Technology Officer, Troy Bryenton.
We are particularly excited about the recent purchase of the Vault Health life sciences platform which will allow us to accelerate development plans we had underway for workflow features such as advanced scheduling, investigational product tracking, and data exchange with electronic data capture and electronic medical records systems. These enhanced capabilities will help us to reduce some of the manual efforts required to execute centralized clinical trials and drive operational efficiencies. With cost containment efforts like these and the previously reported headcount reductions that we announced last quarter, we expect to achieve 2023 EBITDA of negative $48 million to negative $50 million, and we continue to progress toward our objective to reach EBITDA positive and cash flow neutral by the end of 2024 without having to raise additional capital.
With that, I will now turn the call over to Mike Zaranek, our Chief Financial Officer to provide additional detail regarding our financial performance.
Photo by National Cancer Institute on Unsplash
Mike Zaranek: Thank you David, and good morning everyone. I will discuss the fourth quarter results for the period ended December 31, 2022 and then affirm our outlook for the full year 2023. In the fourth quarter, we reported revenues of $15.9 million which represents a 22% decrease from the same period of the prior year; however, it's important to note that if you exclude COVID-related studies from both the fourth quarter of 2021 and 2022 periods, our underlying business continued to expand with fourth quarter revenue growth up 19% year-over-year. As we noted in our fourth quarter earnings release, full year 2022 revenues increased 18% year-over-year. Again, if COVID-related studies were excluded from both the full year '21 and '22 numbers, our revenue growth was up 65% year-over-year.
Consistent with our comments on the quarterly 2022 earnings calls, COVID-related studies represented a much smaller percentage of our revenue for full year 2022 and accounted for a very small percentage of our year-end 2022 backlog. We finished the fourth quarter with $33 million of gross bookings and just under $19 million of net bookings, which represents a significant increase compared to the third quarter. The majority of the difference between the gross and the net bookings was related to a final project reconciliation which occurred in the fourth quarter. You may recall we mentioned on the third quarter earnings release call, we had one study wrap up early due to the customer being able to utilize a lower patient count to prove the trial end points.
The final project reconciliation associated with this project was completed in the fourth quarter, at which point we took the project realization reduction to backlog. Excluding this final reconciliation, actual cancellations during the quarter were insignificant. Adjusted gross margin was 24.5% for the fourth quarter compared to 23.2% for the same period last year. Adjusted gross profit for the fourth quarter was $3.9 million compared to $4.7 million in the same period of the prior year. Now I wanted to provide an update on the cost actions we announced on the third quarter earnings call. We remain on track for the cost reduction plan and realized approximately one month of savings of that annual plan in the fourth quarter. Selling, general and administrative expenses excluding $5.1 million of stock-based compensation was $15.5 million in the fourth quarter, a decrease of $3.7 million versus the third quarter of 2022 due to the restructuring program that we implemented as well as lower variable expenses.
Additionally, selling, general and administrative expenses excluding stock-based compensation declined nearly 41% in the fourth quarter of 2022 versus the fourth quarter of 2021. Adjusted EBITDA, which we calculate by adding back depreciation, amortization, taxes, interest, other income, stock-based compensation, and other non-cash charges, was a loss of $11.6 million in the quarter, representing a $3 million sequential improvement compared to the third quarter of 2022 and a $9.9 million improvement versus the fourth quarter of 2021. On a full year basis, our adjusted EBITDA was negative $62.5 million, which exceeded the 2022 adjusted EBITDA guidance we originally provided during the first quarter 2022 earnings call. In the fourth quarter, we also took a non-cash impairment of $44 million related to our long-lived assets.
Given our operating model is in the early stages of scale and the market capitalization of the company was for a sustained period less than cash and book value, under U.S. GAAP we were required to perform an analysis regarding the recoverability of long-lived asset carrying values as of the balance sheet date. Under U.S. GAAP accounting standards, this analysis we performed concluded an impairment of our long-lived assets was appropriate during the fourth quarter. Again, this was a non-cash charge. We do not view the impairment necessarily as a reflection of the long term business benefits of our software-related projects or the life of our platform, both of which remain robust on our ability to deliver for our customers. To be clear, we remain confident and laser focused on the future returns on our investments in our unified technology stack, which is further enhanced by the bulk purchase which we announced in the first quarter of 2023.
In large part due to the $44 million non-cash impairment, U.S. GAAP net loss was $66.5 million versus a GAAP net loss of $65.1 million in the fourth quarter a year ago. The adjusted net loss for the fourth quarter was $16.9 million, which compared to an adjusted net loss of $23.4 million in the same period last year. Additionally, we ended 2022 with $254 million in federal cumulative net operating loss carry-forwards. Now turning to cash, we ended the quarter with $108.1 million in cash and cash equivalents. In the fourth quarter, our cash burn was approximately $22 million, which included some one-time costs from restructuring and other items of approximately $3 million. Excluding these one-time items, our cash burn improved sequentially quarter-over-quarter.
As a reminder, from a modeling standpoint, annual bonuses are paid to qualifying employees in the first quarter, which will impact our first quarter cash burn this year. Additionally, concurrent with our earnings release, we have filed with the SEC a post-effective amendment and a shelf registration statement. The former was required by the registration rights agreement that we entered into as part of the merger agreement from when we went public, and we view the shelf registration as a prudent financial management tool. Many public companies have an effective shelf registration for this purpose. We began F3 eligible in November of last year and filed the shelf registration this morning. As a reminder, if we were to conduct an offering pursuant to this registration statement, we would be required to file a prospectus supplement for that transaction.
Now let's turn to the outlook for 2023. In light of the challenging business conditions that we continue to experience, we expect 2023 revenues to be in the range of $55 million to $60 million for the full year. Additionally, we expect adjusted EBITDA for 2023 to be between negative $50 million to negative $48 million. As of December 31, we had approximately 116.1 million shares outstanding. As we currently anticipate having a net loss in the upcoming quarter and year, any converted options would be deemed anti-dilutive and therefore on a GAAP basis, we expect basic and diluted share counts to be the same. In summary, we continue to execute for our customers. We delivered underlying growth in the business if you exclude the COVID study-related revenues and exceeded our most recent guidance for the fourth quarter.
We remain committed to delivering long-term profitability to create value for shareholders, and at this point I'd like to turn the call back over to David for closing comments.
David Coman: Thank you Mike. While the environment remains challenging, I'm proud of the focus and resiliency we see across our employees and overall stakeholders. We'll continue to execute on our strategy and deliver value to our customers by driving iterative improvements in our technology and solutions. With that, I will now turn the call over to the Operator to open it up for questions.
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