| INSIDER TRANSACTIONS REPORTED - LAST TWO YEARS |
| Date | Insider | Shares | Type | Transaction | Value* | | 24-Nov-09 | REDDICK ANDREW D Officer | 425,000 | Direct | Option Exercise at $1.30 per share. | $552,500 | | 24-Nov-09 | REDDICK ANDREW D Officer | 249,353 | Direct | Disposition (Non Open Market) at $4.26 per share. | $1,062,243 | | 26-May-09 | MARKHAM RICHARD J Director | 10,000 | Indirect | Sale at $7.38 per share. | $73,800 | | 26-May-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 10,000 | Indirect | Sale at $7.38 per share. | $73,800 | | 22-May-09 | MARKHAM RICHARD J Director | 5,800 | Indirect | Sale at $7.50 per share. | $43,500 | | 22-May-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 5,800 | Indirect | Sale at $7.50 per share. | $43,500 | | 20-May-09 | MARKHAM RICHARD J Director | 6,000 | Indirect | Sale at $7.34 per share. | $44,040 | | 20-May-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 6,000 | Indirect | Sale at $7.34 per share. | $44,040 | | 15-May-09 | MARKHAM RICHARD J Director | 1,338 | Indirect | Sale at $7.04 per share. | $9,419 | | 15-May-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 1,338 | Indirect | Sale at $7.04 per share. | $9,419 | | 13-May-09 | MARKHAM RICHARD J Director | 7,028 | Indirect | Sale at $7.05 per share. | $49,547 | | 13-May-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 7,028 | Indirect | Sale at $7.05 per share. | $49,547 | | 11-May-09 | BOEHM GARTH Officer | 24,000 | Direct | Acquisition (Non Open Market) | N/A | | 11-May-09 | BOEHM GARTH Officer | N/A | Direct | Statement of Ownership | N/A | | 8-May-09 | MARKHAM RICHARD J Director | 10,600 | Indirect | Sale at $6.93 per share. | $73,458 | | 8-May-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 10,600 | Indirect | Sale at $6.93 per share. | $73,458 | | 7-May-09 | MARKHAM RICHARD J Director | 12,900 | Indirect | Sale at $6.91 per share. | $89,139 | | 7-May-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 12,900 | Indirect | Sale at $6.91 per share. | $89,139 | | 6-May-09 | MARKHAM RICHARD J Director | 12,100 | Indirect | Sale at $6.79 per share. | $82,159 | | 6-May-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 12,100 | Indirect | Sale at $6.79 per share. | $82,159 | | 24-Apr-09 | JONES ROBERT B Officer | 45,000 | Direct | Acquisition (Non Open Market) | N/A | | 24-Apr-09 | SEISER ROBERT A Officer | 24,000 | Direct | Acquisition (Non Open Market) | N/A | | 24-Apr-09 | REDDICK ANDREW D Officer | 85,000 | Direct | Acquisition (Non Open Market) | N/A | | 24-Apr-09 | EMIGH JAMES F Officer | 18,000 | Direct | Acquisition (Non Open Market) | N/A | | 24-Apr-09 | CLEMENS PETER A Officer | 30,000 | Direct | Acquisition (Non Open Market) | N/A | | 24-Mar-09 | MARKHAM RICHARD J Director | 35,000 | Indirect | Sale at $7.11 per share. | $248,850 | | 24-Mar-09 | CARE CAPITAL II LLC Beneficial Owner (10% or more) | 35,000 | Indirect | Sale at $7.11 per share. | $248,850 | | 9-Feb-09 | BRZECZKO ALBERT W Officer | 24,000 | Direct | Acquisition (Non Open Market) | N/A | | 9-Feb-09 | BRZECZKO ALBERT W Officer | N/A | Direct | Statement of Ownership | N/A | | 14-Nov-08 | SKELLY WILLIAM G Director | 3,200 | Direct | Sale at $5.01 - $5.05 per share. | $16,0002 | | 7-Apr-08 | JONES ROBERT B Officer | 50,000 | Direct | Acquisition (Non Open Market) | N/A | | 7-Apr-08 | JONES ROBERT B Officer | N/A | Direct | Statement of Ownership | N/A | | 24-Jan-08 | ROSS GEORGE K Director | N/A | Direct | Statement of Ownership | N/A |
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* = Where indicated, some values are estimates. 1 = Potential proceeds estimated by the filer. 2 = Estimated based on the average of multiple prices reported. 3 = Multiple dates reported. Most recent date shown. |
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