| NET SHARE PURCHASE ACTIVITY |
| Insider Purchases - Last 6 Months | | | Shares | Trans | | Purchases | N/A | 0 | | Sales | 3,831,810 | 5 | Net Shares Purchased
(Sold) | (3,831,810) | 5 | | Total Insider Shares Held | 6.18M |
N/A
| % Net Shares Purchased
(Sold) | (38.3%) |
N/A
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| Net Institutional Purchases - Prior Qtr to Latest Qtr | | | Shares | | Net Shares Purchased (Sold) | (10,949,000) | | % Change in Institutional Shares Held | 3218.1% |
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| INSIDER TRANSACTIONS REPORTED - LAST TWO YEARS |
| Date | Insider | Shares | Type | Transaction | Value* | | 10-Sep-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 1,212,106 | Direct | Sale at $2.76 per share. | $3,345,412 | | 6-Aug-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 3,500 | Direct | Sale at $2.03 per share. | $7,104 | | 5-Aug-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 396,000 | Direct | Sale at $2 per share. | $792,000 | | 30-Jul-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 15,600 | Direct | Sale at $1.85 per share. | $28,860 | | 29-Jul-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 113,500 | Direct | Sale at $1.85 per share. | $209,975 | | 28-Jul-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 49,000 | Direct | Sale at $1.85 per share. | $90,650 | | 5-Jun-09 | LEW JENNIFER
Officer | 2,332 | Direct | Statement of Ownership | N/A | | 4-Jun-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 505,000 | Direct | Sale at $1.68 per share. | $848,400 | | 3-Jun-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 1,292,000 | Direct | Sale at $1.99 per share. | $2,571,080 | | 27-Apr-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 22,000 | Indirect | Sale at $1.30 per share. | $28,600 | | 23-Oct-08 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 8,132,657 | Indirect | Statement of Ownership | N/A | | 23-Oct-08 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 4,824,000 | Direct | Statement of Ownership | N/A | | 22-Oct-08 | FLYNN JAMES E
Beneficial Owner (10% or more) | 4,851,538 | Indirect | Sale at $0.22 - $0.28 per share. | N/A | | 9-May-08 | BUC NANCY L
Director | 5,000 | Direct | Purchase at $2.24 per share. | $11,200 | | 6-May-08 | PHILLIPS PEGGY V
Director | 10,000 | Direct | Purchase at $2.35 per share. | $23,500 | | 5-May-08 | PHILLIPS PEGGY V
Director | 33,000 | Direct | Purchase at $2.24 - $2.33 per share. | $75,0002 | | 5-May-08 | DINA DINO
Officer | 40,000 | Direct | Purchase at $2.40 - $2.42 per share. | $96,0002 | | 2-May-08 | PHILLIPS PEGGY V
Director | 2,000 | Direct | Purchase at $1.99 per share. | $3,980 | | 2-May-08 | DINA DINO
Officer | 60,000 | Direct | Purchase at $1.98 - $2.5 per share. | N/A | | 25-Feb-08 | SANDERS MARTIN E
Officer | 8,766 | Indirect | Statement of Ownership | N/A | | 25-Feb-08 | SANDERS MARTIN E
Officer | 25,000 | Direct | Statement of Ownership | N/A | | 20-Dec-07 | CARSON DENNIS
Director | 10,000 | Indirect | Automatic Sale at $5 per share. | $50,000 |
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* = Where indicated, some values are estimates.
1 = Potential proceeds estimated by the filer.
2 = Estimated based on the average of multiple prices reported.
3 = Multiple dates reported. Most recent date shown. |
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Insider Transactions
